WebTherapeutic Effects: Prevention of rejection reactions. Slowed progression of rheumatoid arthritis or psoriasis. Adverse Reactions/Side Effects CNS: SEIZURES, tremor, confusion, flushing, headache, psychiatric problems. CV: hypertension. GI: diarrhea, hepatotoxicity, nausea, vomiting, abdominal discomfort, anorexia, pancreatitis. WebNursing Implications. Assessment & Drug Effects. Observe injection site frequently; if extravasation occurs, stop infusion immediately. Restart infusion in another vein. Report to physician. Institute prompt local treatment to prevent thrombophlebitis and necrosis. Monitor for severe toxic effects that occur with high frequency.
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WebSep 21, 2024 · Cyclophosphamide interferes with oogenesis and spermatogenesis. It may cause sterility in both sexes. Development of sterility appears to depend on the dose of cyclophosphamide, duration … chills without fever with covid
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WebPHYSICAL THERAPY IMPLICATIONS Examination and Evaluation Be alert for signs of cardiomyopathy, including fatigue, dizziness, palpitations, breathlessness with exertion, and peripheral and pulmonary edema. Report these signs to … Assessment & Drug Effects 1. Lab tests: Total and differential leukocyte count, platelet count, and Hct are determined initially and at least 2 times per week during maintenance period. Baseline and periodic determinations of liver and kidney function and serum electrolytes also should be made. … See more Cell-cycle-nonspecific alkylating agent chemically related to the nitrogen mustards. Action mechanism unknown but thought to be the result of cross-linkage of DNA strands, thereby blocking synthesis of DNA, RNA, and … See more To prevent rejection in homotransplantation; to treat severe rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Wegener's granulomatosis, nephrotic syndrome. See more Has pronounced immunosuppressive activity and is a highly toxic drug; thus therapeutic effects are usually accompanied by some evidence of toxicity. See more As single agent or in combination with other chemotherapeutic agents in treatment of malignant lymphoma, multiple myeloma, leukemias, … See more WebOct 28, 2024 · Cyclophosphamide injectable solution often causes nausea, vomiting, and loss of appetite. It can also cause dizziness, blurred vision, and trouble seeing, which could affect your ability to drive... chills with stomach pain